Nervous System Involvement in HIV Infection

Abstract

Neurological involvement in HIV positive patients is very common. These conditions are either caused by direct and indirect infection of brain tissue by HIV virus or secondary to immunodeficiency status produced in HIV positive patients. The Central Nervous System (CNS) involvement varies from neoplasm, opportunistic brain infections to brain diseases resulting from exaggerated immune-reaction. Clinically, they present as diffuse non-focal or focal brain diseases. To decrease the morbidity, it is very important that these conditions are suspected and diagnosed early. Multiple infections should be considered while evaluating these patients.